iCell Microglia Alzheimer's Disease Panel

Human iPSC-derived microglia from an Alzheimer’s disease (AD) cohort. Choose from phenotypically Apparently Healthy Normal (genotype: TREM2 R47H) or symptomatic AD (genotype: APOE 4/4) microglia.
Catalog # iCell Microglia Alzheimer's Disease Panel

Microglia, the resident immune cells of the brain, are key players in neuroinflammation and manifestation of neurodegenerative diseases. Recent studies have identified highly expressed genes in microglia that are associated with increased risk of developing Alzheimer’s disease (AD), propelling microglia to the forefront of neurodegenerative disease progression and emphasizing the critical need of model systems to study microglia.

The limited availability and inconsistency of primary human microglia has constrained research and therapeutic progress. iCell® Microglia, based on technology developed by the Blurton-Jones laboratory (Abud et al. Neuron 2017) for which FUJIFILM Cellular Dynamics Inc. has an exclusive license from the University of California-Irvine, overcome these constraints by offering consistent, high-quality microglia derived from human induced pluripotent stem cells, thus enabling the study of cytokine signaling, synaptic transmission, and plasticity in normal CNS function and during disease progression.

Products

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Grouped product items
Catalog # Description Quantity Type Price  
R1213 iCell Microglia Kit, AD APOE E4/E4, 11995
Female, APOE 4/4, Alzheimer's Disease (AD)

Cell Kit

  • APOE RS429358: C/C
  • APOE RS7412: C/C
  • APOE Genotype: 4/4
  • TREM2 (P.R47H) RS7593268: C/C
  • CD33 RS12459419: C/C
1 Vial: ≥ 1 x 10^6 cells/vial
Included Componenets
  • C1227 Cryopreserved iCell Microglia AD, APOE E4/E4, 11995
  • 50ml iCell Glial Base Medium
  • 0.5ml iCell Microglia Supplement A (100x)
  • 0.5ml iCell Microglia Supplement B (100x)
  • 1ml iCell Neural Supplement C (50X)
  • iCell Microglia Quick Guide
  • Additional reagents required; see Quick Guide
Kit Size
$1,995.00
R1217 iCell Microglia Kit, AHN, TREM2 R47H, 11969
Female, TREM2 R47H, Apparently Healthy Normal (AHN)

Cell Kit

  • APOE RS429358: T/C
  • APOE RS7412: C/T
  • APOE Genotype: 3/3
  • TREM2 (P.R47H) RS7593268: C/T
  • CD33 RS12459419: C/C
1 Vial: ≥ 1 x 10^6 cells/vial
Included Componenets
  • C1231 Cryopreserved iCell Microglia AHN, TREM2 R47H, 11969
  • 50ml iCell Glial Base Medium
  • 0.5ml iCell Microglia Supplement A (100x)
  • 0.5ml iCell Microglia Supplement B (100x)
  • 1ml iCell Neural Supplement C (50X)
  • iCell Microglia Quick Guide
  • Additional reagents required; see Quick Guide
Kit Size
$1,995.00
C1231 iCell Microglia, AHN, TREM2 R47H, 11969
Female, TREM2 R47H, Apparently Healthy Normal (AHN)

Cells only

  • APOE RS429358: T/C
  • APOE RS7412: C/T
  • APOE Genotype: 3/3
  • TREM2 (P.R47H) RS7593268: C/T
  • CD33 RS12459419: C/C
1 Vial: ≥ 1 x 10^6 cells/vial
Included Componenets
  • C1231 Cryopreserved iCell Microglia AHN, TREM2 R47H, 11969
  • X1022 iCell Microglia Quick Guide
  • Additional reagents required; see Quick Guide
Cells Only
$1,595.00
C1227 iCell Microglia, AD APOE E4/E4, 11995
Female, APOE 4/4, Alzheimer's Disease (AD)

Cells only

  • APOE RS429358: C/C
  • APOE RS7412: C/C
  • APOE Genotype: 4/4
  • TREM2 (P.R47H) RS7593268: C/C
  • CD33 RS12459419: C/C
1 Vial: ≥ 1 x 10^6 cells/vial
Included Componenets
  • C1227 Cryopreserved iCell Microglia AD, APOE E4/E4, 11995
  • X1022 iCell Microglia Quick Guide
  • Additional reagents required; see Quick Guide
Cells Only
$1,695.00

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