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iCell Hematopoietic Progenitor Cells 2.0 Kit, 01279
Unlock new insights in blood cell research with iCell® Hematopoietic Progenitor Cells 2.0, derived from human induced pluripotent stem cells (iPSCs).
- Reproducible research Each lot is >80% CD34+/CD43+ and undergoes rigorous quality control to ensure batch-to-batch consistency.
- Physiological relevance Derived from healthy iPSCs, these cells capture key stages of blood cell development for human-relevant research.
- Scalable consistency Generated in large quantities from a single donor, iCell Hematopoietic Progenitor Cells 2.0 eliminate lot-to-lot variability.
- Versatile applications These cells enable targeted drug discovery, hematotoxicity testing, infectious disease research, and more.
- Simplified workflows Cryopreserved and ready to use, iCell® Hematopoietic Progenitor Cells 2.0 help you complete more studies, faster.
$1,345.00
Products
Kits
- Cryopreserved iCell Hematopoietic Progenitor Cells 2.0, 01279
- User’s Guide
- Additional reagents required; see Quick Guide
genetic status
quantity (Cells Per Vials)
catalog #
Catalog #: R1115
iCell Hematopoietic Progenitor Cells 2.0 Kit, 01279
From
$1,345.00
Product Overview
iCell® Hematopoietic Progenitor Cells 2.0 are highly pure multipotent progenitor cells with the ability to differentiate into blood cell lineages. These cells can be consistently generated from human induced pluripotent stem cells in large-scale quantities, thereby overcoming the high variability and limited quantities associated with primary CD34+ cord blood or peripheral blood cells.
Advantages of iCell Hematopoietic Progenitor Cells 2.0
- Reproducible results: High purity (>80% CD34+/CD43+) and rigorous quality control ensure the same performance with every batch.
- Rapid results: Complete more studies in less time with ready-to-use iPSC-derived hematopoietic progenitor cells (HPCs).
- Eliminate donor-to-donor variability: iPSC-derived HPCs can be produced in essentially unlimited quantities from a single donor.
Applications
- Targeted drug discovery
- Hematotoxicity testing
- Erythroid differentiation
- Myeloid lineage differentiation
- Infectious disease studies
Components:
Catalog #R1115
iCell Hematopoietic Progenitor Cells 2.0 Kit, 01279, 1 Vial: ≥ 1 x 10^6 cells/vial
- Cryopreserved iCell Hematopoietic Progenitor Cells 2.0, 01279
- User’s Guide
- Additional reagents required; see Quick Guide
Donor Background
Sex:
MaleRace:
CaucasianCell Type:
Hematopoetic Progenitor CellsSource Line:
01279Modeled Disease Phenotype:
Apparently Healthy NormalDonor Status:
Apparently Healthy NormalTissue Source:
BloodAge At Sampling:
50-59Engineered Line:
NoDisease Status:
Apparently Healthy Normal (AHN)Our regular business hours are 9:00am to 5:00pm Central Time (USA)
Need Help With This Product?
Our specialists are here to help you find the best product for your application.
Our regular business hours are 9:00am to 5:00pm Central Time (USA)
Technical Docs
USER DOCS
Biosafety Document
iCell Hematopoietic Progenitor Cells 2.0 Biosafety Document
Performance Data
iCell Hematopoietic Progenitor Cell Morphology
iCell Hematopoietic Progenitor Cells 2.0 display typical morphology as freely floating round cells.
Figure 1: Morphology of iCell Hematopoietic Progenitor Cells 2.0
Figure 2: iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Express Hematopoietic Progenitor Cell Markers
Expression of Hematopoietic Progenitor Cell Markers
(A, B) Cells analyzed by flow cytometry at thaw are >90%+ for hematopoietic cell surface markers. (C) Percentage of cells expressing hematopoietic cell surface markers after thaw. Data shown as mean ±SEM; n=13.
Generation of Multiple Lineages
iCell Hematopoietic Progenitor Cells 2.0 were plated in colony-forming unit (CFU) assays using a methylcellulose-based medium. (A) Representative images of colonies are shown. (B) CFU frequencies are shown, including erythroid (BFU-E), granulocyte/macrophage (CFU-M, CFU-G, CFU-GM) and mixed colonies (CFU-GEMM). Data shown as mean ±SEM; n=13.
Figure 3: iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Generate Colonies of Multiple Lineages
Publications
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M (2017) Neuron. 94(2):278-293 (2017)