iCell Hepatocytes 2.0

Fuel hepatic research with reliable and relevant human hepatocyte cells. FUJIFILM CDI’s iCell^® Hepatocytes 2.0 are terminally differentiated from induced pluripotent stem cells (iPSCs). These iPSC-derived hepatocytes overcome limitations in functionality, reproducibility, and availability associated with existing tumor-derived and primary cell models, providing a scalable in vitro tool for drug development, hepatotoxicity testing, and health and disease research.

• Consistent quality Populations of >95% pure human IPS hepatocytes ensure highly reproducible biologically relevant results.
• Accurate morphology CDI’s iPSC-derived hepatocytes exhibit characteristic hepatocyte cobblestone morphology, bi-nucleation, and bile canaliculi formation.
• Physiological function With basal and inducible P450 activity, these hepatocyte cells are built to support your pharmacological and toxicological research.
• Defined genotype Investigate genetic influences on drug metabolism and disease mechanisms with hepatocyte cell lines genotyped for >1,900 ADME markers, including all FDA-validated genes.
• Assay compatibility From diabetes research to microtissue engineering and viral replication to hepatotoxicity, iCell Hepatocytes 2.0 have extensive applicability in hepatic research.