iCell Induced Excitatory Neurons

Accelerate drug discovery, toxicity testing, and neurological disease modeling with functional human excitatory neurons. Derived from induced pluripotent stem cells (iPSCs) engineered to overexpress neurogenin-2, iCell^® Induced Excitatory Neurons deliver reliable insights into neuronal function in health and disease.

With highly pure populations and off-the-shelf and custom disease models available, you can rely on iCell Induced Excitatory Neurons to power your neurological research.

• Reliable performance Populations of >90% pure glutamatergic neurons stably express characteristic receptors (AMPA) and transporters (vGLUT1 and vGLUT2) for ≥2 weeks in monoculture.
• Fast recovery These iPSC-derived excitatory neurons arrive fully differentiated and develop branched networks within 2-3 days of plating, allowing seamless integration into your workflow.
• Co-culture suitability iCell Induced Excitatory Neurons reliably develop active neural networks when co-cultured with isogenic iCell Astrocytes 2.0 in 2D or 3D.
• Versatile functionality Advance your neurodevelopment, neurodegeneration, and drug discovery research with iPSC-derived excitatory neurons that display robust and synchronous multielectrode array (MEA) activity and sensitivity to neurotoxins.
• Optimal value Increase throughput and decrease cost per experiment with one vial of excitatory neurons (6x10⁶ cells) seeding up to three 96-well plates.