Patents and Use Restrictions

Reprogramming Related

Products are covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,298,825, 8,440,461, 8,546,140, 8,609,417, 8,691,574, 8,741,648, 8,765,470, 9,175,268, 9,295,697, 9,328,332, 9,347,044, 9,447,382, 9,644,184, 10,106,772 and corresponding foreign patents. Additional patents are pending.

iCell® Astrocytes (ASC-100-020-001-PT, R1092)

Product is covered by US Patent Nos. 7,250,294, 8,148,148, 8,183,038, 8,252,586, 8,440,461, 8,609,417, 9,487,752 and corresponding foreign patents. Additional patents are pending.

iCell Cardiac Progenitor Cells (CPC-301-020-001-PT, R1093)

Product is covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,691,574, 8,741,648, 9,328,332, 9,644,184, 9,663,764, 10,077,428 and corresponding foreign patents. Additional patents are pending.

iCell Cardiomyocytes and iCell Cardiomyocytes2 (CMC-100-010-001,CMC-100-010-005, CMC-100-110-001, CMC-100-110-005,CMC-100-012-000.5, CMC-100-012-001, R1007, R1017, R1057, R1105, R1106 R1117, R1132)

Products are covered by US Patent Nos. 7,851,167, 8,183,038, 8,440,461, 9,365,826, 9,365,827, 9,957,482 and corresponding foreign patents. Additional patents are pending.

iCell DopaNeurons (DNC-301-030-001, R1088, R1032)

Product is covered by US Patent Nos. 6,534,261, 6,607,882, 6,746,838, 6,794,136, 6,824,978, 6,866,997, 6,933,113, 6,979,539, 7,013,219, 7,030,215, 7,220,719, 7,241,573, 7,241,574, 7,250,294, 7,892,830, 8,048,999, 8,148,148, 8,153,428, 8,183,038, 8,257,941, 8,252,586, 8,268,620, 8,546,140, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,487,752, 9,644,184, 9,694,036, 9,750,768 and corresponding foreign patents. Additional patents are pending.

iCell Endothelial Cells (ECC-100-010-001, R1022)

Product is covered by US Patent No. 8,183,038, 8,440,461, 8,557,580 and corresponding foreign patents. Additional patents are pending.

iCell GlutaNeurons (GNC-301-030-001, R1034)

Product is covered by US Patent Nos. 6,534,261, 6,607,882, 6,746,838, 6,794,136, 6,824,978, 6,866,997, 6,933,113, 6,979,539, 7,013,219, 7,030,215, 7,220,719, 7,241,573, 7,241,574, 7,250,294, 7,892,830, 8,048,999, 8,148,148, 8,183,038, 8,257,941, 8,252,586, 8,268,620, 8,546,140, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,487,752, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell Hematopoietic Progenitor Cells (HPC-301-020-001-PT, R1094)

Product is covered by US Patent Nos. 6,218,185, 6,534,261, 6,607,882, 6,746,838, 6,794,136, 6,824,978, 6,866,997, 6,933,113, 6,962,810, 6,979,539, 7,013,219, 7,030,215, 7,105,343, 7,220,719, 7,241,573, 7,241,574, 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,691,574, 8,741,648, 9,328,332, 9,574,179, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell Hepatoblasts (HBC-100-020-001-PT, R1096)

Product is covered by US Patent Nos. 6,506,574, 7,473,555, 7,510,876, 7,541,185, 7,625,753, 7,989,204, 8,148,151, 8,183,038, 8,283,168, 8,440,461, 8,445,273, 8,574,905 and corresponding foreign patents. Additional patents are pending.

iCell Hepatocytes and iCell Hepatocytes 2.0 (HCC-100-010-001, PHC-100-020-001-PT, R1027)

Product is covered by US Patent Nos. 6,506,574, 7,473,555, 7,510,876, 7,541,185, 7,625,753, 7,989,204, 8,148,151, 8,183,038, 8,283,168, 8,440,461, 8,445,273, 8,574,905, 9,745,553 and corresponding foreign patents. Additional patents are pending.

iCell Macrophages (MAC-301-010-001-PT, R1099)

Product is covered by US Patent Nos. 6,218,185, 6,534,261, 6,607,882, 6,746,838, 6,794,136, 6,824,978, 6,866,997, 6,933,113, 6,962,810, 6,979,539, 7,013,219, 7,030,215, 7,105,343, 7,220,719, 7,241,573, 7,241,574, 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,609,417, 8,691,574, 8,741,648, 9,328,332, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell Mesenchymal Stem Cells (MSC-301-010-001-PT, R0198)

Product is covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,609,417, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell GABANeurons (NRC-100-010-001, R1013, R1084, R1011)

Product is covered by US Patent Nos. 7,250,294, 8,148,148, 8,183,038, 8,252,586, 8,440,461, 8,609,417, 9,487,752 and corresponding foreign patents. Additional patents are pending.

iCell Microglia (R1131)

Product is covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,609,417, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell Motor Neurons (MNC-301-030-001-PT, R1051, R1049)

Product is covered by US Patent Nos. 7,250,294, 7,892,830, 8,048,999, 8,148,148, 8,183,038, 8,252,586, 8,257,941, 8,268,620, 8,546,140, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,453,198, 9,644,184 and corresponding foreign patents. Additional patents are pending.

iCell Retinal Pigment Epithelial Cells (R1101, R1102, R1113)

Product is covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,546,140, 8,609,417, 8,691,574, 8,741,648, 9,175,268, 9,328,332, 9,644,184 and corresponding foreign patents. Additional patents are pending.

MyCell® Products (iPSC, iPSC-ENG, iPSC-CM, iPSC-NC, iPSC-EC, iPSC-HC, iPSC-CP)

Products are covered by US Patent Nos. 7,892,830, 8,048,999, 8,183,038, 8,257,941, 8,268,620, 8,298,825, 8,546,140, 8,603,818, 8,691,574, 9,213,999, 9,279,103, 9,279,107, 9,295,697, 9,328,332, 9,499,786, 9,644,184, 9,644,186, 9,745,553, 9,750,768 and corresponding foreign patents. Additional patents are pending. In addition, for MyCell Products that also involve the manufacture of differentiated cells, one or more of the patents associated with the particular cell type listed above may also be applicable.

Specific products may be subject to additional third-party licenses or use restrictions (e.g., limited use label licenses) and can be found here.