For years researchers have used 3D cell culture to create more biologically relevant cell systems for screening, and 3D neurospheres using iPSC-derived materials have provided a great case study for this. iCell® NeuroSpheres offer an immediate, versatile, and reproducible way to incorporate 3D neural spheroids into your disease and drug discovery research. Mix any combination of iCell neuronal cells (multiple subtypes available) and iCell Astrocytes to generate your desired brain region-specific neurosphere for use in high throughput assays, including calcium imaging.
iCell NeuroSpheres are already making headlines! An exciting new publication by Marc Ferrer at the National Center for Advancing Translational Sciences (NCATS) showcased the spheroid’s versatility, ease-of-use, and ability to incorporate iCell neural disease models.
Benefits of creating iCell NeuroSpheres:
- In stock – Uses off-the-shelf iCell neuronal and glial cells
- Consistent – Generates reproducible sphere size and cell type ratios
- Flexible - Creates brain region-specific spheres
- Disease-relevant - Amenable to disease and neuroinflammation modeling
- High throughput – Generates one sphere per well in a 384-well format
- Reliable – Scalable iCell manufacturing, with industry-leading cell quality
