eNewsletters

Issue highlights

Trending:

Due to its popularity last year, we've brought back our promotion for iCell Induced Excitatory Neurons and added a second promotion for iCell Microglia! Cash in on these deals while supplies last!

 Events:

• SLAS 2025 (January 25-29)
• SOT 2025 - (March 16-20)
• AD/PD 2025 (April 1-5)

Applications:

• NEW POSTER: Assessment of AMX0114, An Antisense Oligonucleotide Targeting Calpain-2, in Multiple Models of Axonal Degeneration (featuring iCell Motor Neurons)
• NEW POSTER: Human iPSC-derived Macrophages Provide Functional Reproducibility with a Rapid Time to Assay

Publications:

Issue highlights

Trending:

With demonstrated low spontaneous activity using both patch clamp and multielectrode array (MEA) methods, iCell Sensory Neurons enable mechanistic studies of sensory hypersensitivity and related sodium channel disorders.

 Events:

• Axxam Webinar - September 17th
• SPS 2024 (September 22-25) San Diego, CA
• SFN 2024 (October 5-9) Chicago, IL
• Pain Conference 2024 (October 28-29) Boston, MA
• SITC 2024 (November 6-10) Houston, TX

Applications:

• NEW APPLICATION: Generation of 3D iCell CardioSpheres with iCell Products
• NEW POSTER: Evaluating Transduction Efficiencies of AAV Vectors into Human iPSC-derived Cell Types

Publications:

Issue highlights

Trending:

• Interview: New Opportunities for Human Stem Cells in Research and Clinical Applications
• iPSC-derived Sensory Neurons with Low Spontaneous Activity
• NEW PRODUCT: Quiescent iPSC-derived Cardiac Fibroblasts with the Ability to Proliferate and Activate

 Events:

• SOT 2024 (March 10-14th) Salt Lake City, UT
• Wisconsin Stem Cell Symposium (April 17th) Madison, WI
• Membrane Physiology Symposium (April 22-23rd) Napa, CA
• ASGCT 2024 (May 7-11th) Baltimore, MD

Applications:

• PROTOCOL: Measuring Microglia Phagocytosis: Kinetic Imaging on the IncuCyte
• NEW APPLICATION: Using iCell Macrophages 2.0 for Liver Immune Component Co-culture

Publications:

• Transcriptional characterization of iCell Microglia as a model for neurodegeneration and therapeutic development.
  Ramaswami G., et al. Scientific Reports, 2024; 14:2153
• Strengthening cardiac therapy pipelines using human pluripotent stem cell-derived cardiomyocytes.
  Raniga K., et al. Cell Stem Cell, 2024, doi.org/10.1016/j.stem.2024.01.007
• Machine learning identifies phenotypic profile alterations of human dopaminergic neurons exposed to bisphenols and perfluoroalkyls.
  Di Credico A., et al. Scientific Reports, 2023; 13(1):21907

Issue highlights:

News

• iCell^® Induced Excitatory Neurons and iCell Macrophages 2.0 Now Available!
• Save the Date! iForum™ Innovation Showcase Webinar coming Jan 30th, 2024.

Events:

• FCDI to Present at SLAS 2024
• Visit Us at the Annual SOT 2024 Meeting
• Neuroscience 2023 Posters are Now Available to Download!
• New Webinar Now Available On-Demand: "Assaying with iPSC-derived Cardiomyocytes: Setting the Rhythm for Early Drug Discovery"

Application Protocols:

• Contractility Analysis of iCell^® Cardiomyocytes²: Evaluating iCell Cardiomyocytes² Co-culture with iCell Cardiac Fibroblasts on the FLEXcyte 96 System
• Measuring Neural Network Activity on MEA: Co-culture of iCell Induced Excitatory Neurons with iCell Astrocytes 2.0

Publications:

• Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology