The CIRM iPSC Repository is a collection of induced pluripotent stem cell lines (iPSC) produced from tissue samples obtained from thousands of individuals by researchers in California through funding from the California Institute of Regenerative Medicine (CIRM). This repository provides researchers with access to iPSC lines for research studies that will enhance the understanding of disease development and progression, thus facilitating the discovery and testing of new drugs and treatments. The size of the collection makes it a powerful resource for studying genetic variation between individuals from diverse backgrounds, helping researchers to understand how disease and treatment may vary in a diverse population. What makes these iPSC lines unique?
- Non-integrating episomal reprogramming
- Reprogramming and quality control performed by a single entity
- Cell line provenance. Each iPSC line in the collection links to a source deidentified tissue sample
- Consents and Commercial Licenses readily available
- Demographic and clinical data available